Sub-chronic safety evaluation of ayurvedic immunostimulant formulation ′immuforte′ in rats in reverse pharmacology
نویسندگان
چکیده
منابع مشابه
Safety evaluation of mercury based Ayurvedic formulation (Sidh Makardhwaj) on brain cerebrum, liver & kidney in rats
BACKGROUND & OBJECTIVES Sidh Makardhwaj (SM) is a mercury based Ayurvedic formulation used in rheumatoid arthritis and neurological disorders. However, toxicity concerns due to mercury content are often raised. Therefore, the present study was carried out to evaluate the effect of SM on brain cerebrum, liver and kidney in rats. METHODS Graded doses of SM (10, 50, 100 mg/kg), mercuric chloride...
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چکیده: یکی از دوره های مهم تاریخی ایران به لحاظ تأمین استقلال ملی مذهبی و حتی تأثیر آن بر فرهنگ و مذهب ایرانیان، دوره صفویه است. رسمیت دادن و رواج مذهب شیعه توسط شاه اسماعیل اول، یکی از مهمترین اقدامات این دولت محسوب می شود. بنابراین برای اجرای این سیاست، وی منصب صدارت را به عنوان منصبی مذهبی- حکو متی ایجاد کرد .این منصب از دوره ی تیموریان ایجاد شده بود ولی در اواخر این دوره اهمیت بیشتری یافت...
15 صفحه اولSub-Chronic Toxicity Study of Alpha-Cypermethrin in Rats
Alpha-cypermethrin (?-CP) a synthetic pyrethroid (type-II) insecticide, dissolved in dimethyl sulfoxide (DMSO-1ml) given consecutive daily orally for 60 days at 1/10LD50 (14.5mg/kg). The animals were sacrificed on day 61st. Biochemicals, cytochromeP450, b5 contents in liver along with antioxidant status, tissue residual concentration, and brain GABA level were studied. It increased the serum am...
متن کاملReverse pharmacology of Ayurvedic drugs includes mechanisms of molecular actions
Sir, In his article “Beyond reverse pharmacology: Mechanism based screening of Ayurvedic drugs,” Dr. R. D. Lele, the eminent teacher of modern medicine and scholar of Ayurveda, urges us to include advances in biomedical sciences for screening of Ayurvedic drugs.[1,2] However, as he has not cited any of the original articles and references on Reverse Pharmacology (RP),[3-7] it seems that the exp...
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ژورنال
عنوان ژورنال: Toxicology International
سال: 2013
ISSN: 0971-6580
DOI: 10.4103/0971-6580.111543